Transient Erythroblastopenia of Childhood
Topic: Transient Erythroblastopenia of Childhood
- Can other children in a family get this illness?
The cause(s) of this illness in otherwise normal children is unknown. It is very rare for other family members to be affected. It is appropriate to reassure parents with regard to this issue.
- Are transfusions always necessary?
No. Only in cases of heart failure is a transfusion necessary. Most often, children can be managed with watchful waiting.
- How can transient erythroblastopenia of childhood be distinguished from Diamond–Blackfan syndrome?
Children with Diamond–Blackfan syndrome are usually <1 year old and can have elevated hemoglobin F levels. If a bone marrow aspirate is obtained during the recovery phase of transient erythroblastopenia of childhood, the diagnosis will be clear. Often, however, only time will tell. Children with transient erythroblastopenia of childhood always recover; those with Diamond–Blackfan syndrome do not.
(Modified from 5-Minute Pediatric Consult book)